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研究アッセイ / スクリーニングサービス

機能ゲノミクススクリーニング  
Arrayed CRISPRko screening in primary human regulatory B cells
ELRIG Networking Event – 2020
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Pooled and arrayed CRISPRko screens in primary human immune cells
ELRIG Networking Event – 2019
PDF
CRISPR screening in xenograft models for in vivo drug MOA analysis

AACR – 2019

PDF
RNA-based screens in primary human immune cells

AACR – 2019

PDF
Dual CRISPRi and CRISPRa screening reveals phenotypic switches in BRAF inhibition
AACR – 2018
PDF
Cell based screens for immuno-oncology discovery research

2018

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Biomarker-based pooled CRISPR-Cas9 screening: Platform development and validation
AACR – 2017
PDF
Cell panel screening  
Cell line panel drug screening in organoids and 3D systems

AACR – 2019

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ATL313, A Potent, and Selective A2A Agonist as a Novel Drug Candidate for the Treatment of Multiple Myeloma

ASH – 2010

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ゲノム編集試薬 /遺伝子発現調節試薬

Synthetic guide RNA for functional gene knockout

Keystone Symposia 2020 – Engineering the Genome

PDF
Development of synthetic guide RNA libraries for CRISPR-mediated transcriptional activation screening for gain-of-function studies

AACR – 2019

PDF
Arrayed synthetic CRISPR libraries are a powerful resource for gene knockout or gene activation screening

Keystone Symposia on Mol. and Cell. Biology2018

PDF
2’-O-methyl phosphorothioate linkage modified synthetic guide RNAs for efficient CRISPR-Cas9 genome editing and reduced cellular toxicity

Keystone Conference2018

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Potent transcriptional activation using CRISPRa with synthetic crRNA

ASCB/EMBO Conference2017

PDF

CRISPR-Cas9 genome editing utilizing chemically synthesized RNA

TIDES2016

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Homology-directed repair with Edit-R CRISPR-Cas9 and single-stranded DNA oligos

FASEB2015

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In vitro and in vivo CRISPR gene editing with MAD7 PDF
CRISPR-mediated transcriptional activation with synthetic guide RNA PDF

Simultaneous gene knockout and transcriptional activation using S. pyogenes VPR-Cas9 mRNA

PDF

カスタムオリゴ合成

The Chemical Synthesis of Long and Highly Modified RNA using 2′-ACE Chemistry

2015

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An efficient method for the Incorporation of molecular probes at multiple/specific sites in RNA: levulinyl protection for 2’-ACE, 5’-silyl oligoribonucleotide synthesis

2015

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遺伝子検査用標準サンプル

Development of cfDNA reference standards that are compatible with commonly used extraction methods and molecular assays

TriCon – 2020

PDF
A comparison of different formats of DNA reference standards commutable with solid and liquid biopsy samples for cancer genomic profiling.

TriCon – 2020

PDF
Development and evaluation of cell line-derived FFPE reference material for MSI assay validation

AACR – 2019

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Comparison of cfDNA Reference Material Prepared using Enzymatic Fragmentation or Sonication for the Validation of Liquid Biopsy Assays

AMP Annual Meeting – 2018

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Reference Standards for the validation of myeloid sequencing assays
ASHG – 2018
PDF

CHOSOURCE™ GSノックアウトCHO発現プラットフォーム

CHOSOURCE™+ ATUM’s Leap-In Transposase

TriCon – 2020

PDF