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Cytotoxic activity test

ADCC and CDC Assays

Based on its expertise in Cell Panel screening, Horzion provides analysis and interpretation of cytotoxic effects in the development pipeline with highly reproducible complement-dependent cytotoxic activity (CDC) assays, NK cell antibody-dependent cytotoxic activity (ADCC) assays.


How do I perform ADCC and CDC assays for Horizon?

ADCC/CDC Assay Services Overview: Add a single agent or combination of development pipelines to evaluate tumor cells by release of calcaine.



How can ADCC/CDC assays advance research in the development pipeline?

384-well assays: large-scale screening with automated, robust, and reproducible high-throughput assays

Single agent or drug combination: Flexible assay design that can be easily customized to fit your project

Multiple donors: Highly enriched NK cells from multiple donors are used to address cross-donor variability

Extensive collection of more than 800 human tumor cell lines targeting the cell surface antigens of interest

More than 10 years of combination screening experience: Analyze and interpret expert data using proprietary Chalice Analyzer software