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Flexible genetically modified cell line generation services on request


From target identification to preclinical studies. It can be used to confirm the target ~ understand the impact of disease-related gene mutations ~ evaluate the treatment method. Our experienced cell line engineering team is available to discuss your requirements.

Supports a wide range of gene modifications and cell types:


​Deletion ​​Reporter/Tag*


​Big Coding Knock-In ​​Conditional Knockout/Knock-in


​Multiplex Editing ​​Lentiviral expression


​Scarless Edit ​​Induction Models/Configuration Models


​Expression cassette integration  ​​Editing of iPSCs or primary T cells

​(to safe harbor site or random)


* Turbo GFP, Turbo RFP, HiBiT, LgBiT, NanoLUC

You can provide us with your own cell lines and perform genetic modifications at no additional cost. Or you can choose from hundreds of licensed cell lines.


Engineering begins immediately after the project plan is agreed upon.

  • Smooth manufacturing process with in-house production automation
  • Flexible manufacturing capabilities to minimize project delays


To start a project:

  1. Build your cell model – Fill out a simple online form with your requirements.
  2. Receive a project quote by email.
  3. The project will be reviewed in detail in Horizon.
  4. After the project is agreed, we will start engineering.


Supported by a dedicated project management team

  • Bringing in cell lines
  • Monthly updates on project progress
  • Final Report
  • Moving to the next step


We can confidently provide you with everything you need.

  • To avoid clone bias, we usually provide 2 clones. It also comes with a parent cell line that is a wild-type control.
  • As standard, we will prepare a final project report and provide you with the following contents:
  • Sequence Checking
  • Mycoplasma and Sterility Tests
  • IP and license packages as required


Our team of experts is available to discuss your cell line engineering requirements.

Please contact Horizon Discovery Inc. first.